You need to add more details.
In the early days with Nero Version 4 and 5 you were able to use DVD Shrink and Nero together. In other words you Shrink your file and Automaticlly burn to disc. The Author of Shrink stopped updating the program and went to work for Nero (Ahead) and wrote Nero's Recode.
If you use Shrink, store the file on Hardrive and then burn with Nero versions 6, 7 and 8.
Otherwise Here's a long, technical explanation as to why you might NOT want to use DVDShrink and Nero together:
http://www.digital-digest.com/~bluta...pgcedit_v2.htm
Basically neither DVDShrink nor Nero put 32k gap blocks between BUPs and IFOs. What that means for you is that the entire reason that BUPs exist is to provide backup info in case an IFO block gets corrupted. Putting them in the same block means that if that block goes bad, your DVD is unreadable. It's a very effective way to defeat the entire reason that BUPs exist in the first place. Thanks Nero - not.
Granted the probability of this happening (that particular block going bad) is low, but it could happen. There is no logical reason to do this. The best method to use DVDShrink, which takes more time, is to use DVDShrink, then create an ISO with PgcEdit, then burn it with ImgBurn.